Trying to Predict Shelf-Life for DrugsJuly 6th, 2012
The pharmaceutical industry spends a lot of money determining and validating the shelf life of drugs. The standard protocol involves keeping drugs in stability chambers and sampling them for chemical changes over a range of time periods—perhaps every month for a year, for example. Researchers at the University of Belgrade in Serbia are trying to develop a mathematical model that will predict the shelf life. They used a generalized regression neural network to predict the shelf life of extended-release aspirin formulations, then validated those results against actual stability chamber measurements.
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