Much of today’s medical research concentrates on identifying the signalling chain within living organisms. Some external molecule triggers a channel opening into a cell which releases a second molecule from the interior of the membrane which in turn begins a chemical cascade of events that change the metabolic state or physical configuration of the cell. Read More
The Problem with Blood Transfusions: The Wrong Blood is Bad
Blood transfusions save millions of lives. Trauma victims or surgery patients who lose significant amounts of blood need replacements to have a decent chance of survival. There’s just one problem. It’s got to be the right blood. As outlined in a 1999 review, transfusing the wrong blood can be deadly. It doesn’t happen often, but Read More
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Herbicide Resistant Crops Reduce Runoff, If Weeds Don’t Play the Game
One of the more puzzling aspects of political resistance to genetically-modified organisms is the uproar over herbicide-resistant crops. Use of crops resistant to glyphosate has allowed farmers to adopt no-tillage or reduced-tillage practices that reduce herbicide runoff and topsoil degradation. It’s really a positive environmental impact. One argument that will always be true when doing Read More
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The Ongoing Effort to Extend the Life of Donated Blood
For as much as medical science has progressed in the last decades, units of donated blood used today have the same six-week shelflife in the blood bank refrigerator as they had in World War I. Alternative methods have been tried to extend the lifetime of donated blood and ease the logistical burden on blood banks. Read More
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Lab Refrigerators and Freezers for Optimum Product Protection
Superior construction, monitoring and alarming features characterize these top-line lab refrigerators and freezers. Read More
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Tracking Down the Source of Erythrocyte Assay Differences
This 1989 report from Dutch researchers provides interesting insight into practical applications of the scientific method. Given a wide variation in erythrocyte sedimentation rate assays on different blood samples, they hypothesized that perhaps transport via car was a contributing factor to the measured variation. They collected samples, stored them briefly in the laboratory refrigerator. The Read More
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Steps to The Present: Preserving Vascular Segments
This is another of the articles we’ve run across that go into the “how we got here” category. This one is a 1948 article on the preservation of vascular segments for later transplant. The article evaluated six different methods of storage, specifically looking at their viability in tissue culture. They found that placing the segments Read More
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Steps to the Present: Method for Full-Length RNA Transcription
We’re living in a time when undergraduate biology students can perform nucleic acid manipulations that were not even dreamed of by their forebears. Those capabilities did not magically appear, they have been developed step-by-step year-after-year. This brief 1990 paper from a University of Texas researcher is an example of the kind of work necessary to Read More
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When is Stem Cell Therapy Ineffective, and Why?
Stem cell therapy holds a lot of promise, but that promise will only be realized if the grunt work is done: careful investigation of the factors that make stem cell grafts effective or ineffective. That’s the kind of work you’ll find in a 2010 report from a multi-institution team of Mexican medical researchers. They investigated Read More
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How to Minimize Herbicide Runoff and Maximize Environmental Health
Herbicides are plant poisons. When “leftover” herbicides run off from the fields they were intended for, they contaminate surface water. That’s not just a casual concern, it can be a deadly influence in the environment. In addition to killing plants directly, the poison can propagate up the food chain and endanger other species. So minimizing Read More
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